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In a further embodiment, the tetracycline compounds of the invention are used to treat disorders described in US!

• Cordero MD, Moreno-Fernández AM, Gomez-Skarmeta JL, de Miguel M, Garrido-Maraver J, Oropesa-Avila M, Rodríguez-Hernández A, Navas P, Sánchez-Alcázar JA.

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Tissue tropism of Escherichia coli adhesins in human extraintestinal infections! This is probably related to the release of adrenal corticosteroids and/or epinephrine secondary to pain!
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